Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Cough
ADR ID BADD_A01105
ADR Hierarchy
22      Respiratory, thoracic and mediastinal disorders
22.02      Respiratory disorders NEC
22.02.03      Coughing and associated symptoms
22.02.03.001      Cough
Description A disorder characterized by sudden, often repetitive, spasmodic contraction of the thoracic cavity, resulting in violent release of air from the lungs and usually accompanied by a distinctive sound. [CTCAE] A sudden, audible expulsion of air from the lungs through a partially closed glottis, preceded by inhalation. It is a protective response that serves to clear the trachea, bronchi, and/or lungs of irritants and secretions, or to prevent aspiration of foreign materials into the lungs. [MeSH]
MedDRA Code 10011224
MeSH ID D003371
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Cough | Cough increased | Cough nonproductive | Cough resembling asthma | Coughing | Dry cough | Irritant cough | Irritative cough | Nocturnal cough | Persistent dry cough | Persistent non-productive cough | Cough aggravated | Coughing after drug inhalation | Drug-induced cough | Smoker's cough | Paroxysmal cough | Acute cough | Chronic cough | Persistent cough | Painful cough | Cough ineffective | Cough weak | Coughs
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
B2 bradykinin receptorP30411T23714
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D02419Rosiglitazone--
BADD_D02423Fondaparinux--
BADD_D02424Valaciclovir--
BADD_D02425Enalapril0.001071%
BADD_D02426Ibandronate--
BADD_D02431Colesevelam0.003054%
BADD_D02432Glycopyrronium0.047909%
BADD_D02433Salbutamol0.000825%
BADD_D02434Cinacalcet--
BADD_D02436Atorvastatin--
BADD_D02437Diclofenamide0.001044%
BADD_D02438Enoxaparin--
BADD_D02439Levodopa0.020715%
BADD_D02440Lisdexamfetamine--
BADD_D02441Rasagiline--
BADD_D02443Tiotropium0.015089%
BADD_D02445Solifenacin0.002316%
BADD_D02446Prasterone0.008727%
BADD_D02448Lorcaserin--
BADD_D02451Pimavanserin--
BADD_D02452Icatibant-
BADD_D02453Midostaurin--
BADD_D02454Panobinostat--
BADD_D02456Vilazodone--
BADD_D02464Fingolimod0.142432%
BADD_D02465Aclidinium0.003979%
BADD_D02467Naloxegol--
BADD_D02468Cannabidiol--
BADD_D02470Nintedanib0.016517%
BADD_D02471Oxygen0.011662%
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